Publications

Grigsby D, Klingeborn M, Kelly U, Chew LA, Hester CG, Asokan A, Devlin G, Smith S, Keyes L, Timmers A, Scaria A, & Bowes Rickman C. Invest Ophthalmol Vis Sci. 2023 Jul 3;64(10):25. doi: 10.1167/iovs.64.10.25.

 

Chew LA, Jun AS, Barnett BP. Corneal endothelial transplantation from bench to bedside: A review of animal models and their translational value for therapeutic development. Exp Eye Res. 2022 Nov;224:109241. doi: 10.1016/j.exer.2022.109241

 

Chew LA, Iannaccone A. Gene-agnostic approaches to treating inherited retinal degenerations. Front Cell Dev Biol. 2023 Apr 13;11:1177838. doi: 10.3389/fcell.2023.1177838.

 

Scalabrino ML, Thapa M, Chew LA,…& Field GD. Robust cone-mediated signaling persists late into rod photoreceptor degeneration. Elife. 2022 Aug 30;11:e80271. doi: 10.7554/eLife.80271

 

Chew, L.A. & Khanna, R. (2018). CRMP2 and voltage-gated ion channels: potential roles in neuropathic pain. Neuronal Signal. 2(1). pii: NS20170220. doi: 10.1042/NS20170220.

 

Chew LA, Bellampalli SS, Dustrude ET, Khanna R.  (2019). Mining the Nav1.7 interactome: Opportunities for chronic pain therapeutics. Biochem Pharmacol. 163:9-20. doi: 10.1016/j.bcp.2019.01.018.

 

Cai S, Moutal A, Yu J, Chew LA.,…& Khanna R. Selective targeting of NaV1.7 via inhibition of the CRMP2-Ubc9 interaction reduces pain in rodents. Sci Transl Med. 2021 Nov 10;13(619):eabh1314. doi: 10.1126/scitranslmed.abh1314.

 

Moutal, A., Chew, L. A., … & Khanna, R. (2016). (S)-Lacosamide inhibition of CRMP2 phosphorylation reduces postoperative and neuropathic pain behaviors through distinct classes of sensory neurons identified by constellation pharmacology. PAIN. 2016 Jul;157(7):1448-1463. doi: 10.1097/j.pain.0000000000000555.

  

Xie, J.Y., Chew, L.A., … & Khanna, R. (2016). Sustained relief of ongoing experimental neuropathic pain by a CRMP2 peptide aptamer with low abuse potential. PAIN. 2016 Sep;157(9):2124-2140. doi: 10.1097/j.pain.0000000000000628.

 

Moutal, A., François-Moutal, L., Perez-Miller, S., Cottier, K., Chew, L. A., … & Khanna, R. (2015). (S)-Lacosamide Binding to Collapsin Response Mediator Protein 2 (CRMP2) Regulates CaV2. 2 Activity by Subverting Its Phosphorylation by Cdk5. Molecular neurobiology, 1-18.

 

Ibrahim, M., Patwardhan, A., Gilbraith, K.B., Moutal, A., Yang, X., Chew, L.A., …& Khanna, R. (2016). Long-lasting antinociceptive effects of green light in acute and chronic pain in rats. PAIN.

 

Moutal, A., Yang, X., Li, W., Gilbraith, K.B., Luo, S., Cai, S., François-Moutal, L., Chew, L.A., … & Khanna, R. (2017). CRISPR/Cas9 editing of Nf1 gene identifies CRMP2 as a therapeutic target in neurofibromatosis type 1 (NF1)-related pain that is reversed by (S)-Lacosamide. PAIN.

 

Moutal, A., Wang, Y., Yang, X., Ji, Y., Luo, S., Dorame, A., Bellampalli, S.S., Chew, L.A… & Khanna, R. (2017). Dissecting the role of the CRMP2-Neurofibromin complex on pain behaviors. PAIN.

 

Khanna R, Yu J, Yang X, Moutal A, Chefdeville A, Gokhale V, Shuja Z, Chew LA,… & Khanna M.  (2019). Targeting the CaVα-CaVβ interaction yields an antagonist of the N-type CaV2.2 channel with broad antinociceptive efficacy. Pain. 160(7):1644-1661. doi: 10.1097/j.pain.0000000000001524.

 

Khanna R, Patwardhan A, Yang X, Li W, Cai S, Ji Y, Chew LA, … & Ibrahim MM.  (2019). Development and Characterization of An Injury-free Model of Functional Pain in Rats by Exposure to Red Light. J Pain. doi: 10.1016/j.jpain.2019.04.008.

 

Myers, C.E., Hoelzinger, D.B., Truong, T., Chew, L.A., Myles, A., Chaudhuri, L., Egan, J.B., Liu, J., Gendler, S.J., & Cohen, P.A.  (2017) Chemotherapy can induce weight normalization of morbidly obese mice despite undiminished ingestion of high fat diet. OncoTarget. 2017 Jan 17;8(3):5426-5438. doi: 10.18632/oncotarget.14576.